Barry Kay Awards
This prestigious Award recognizes Professor Kay’s national and international research contributions to the field of allergy and asthma, which have inspired so many young Allergists and Chest Physicians.
There are six categories for this Award – Basic Science, Adult Allergy, Paediatric Allergy, Primary Care, Allied Health and Undergraduate. The 2017 winners for each category are listed below. To read a summary of the Award-winning abstracts, please click here. To read the abstracts in full, please download the list of 2017 accepted abstracts:
Category: Adult Clinical
Winner: Dr Kok Loong Ue, Guy’s & St Thomas’ Hospital, UK
Title: “Basophil histamine release assay predicts response and time of response to omalizumab in severe chronic spontaneous urticaria”
Poster number: O.005
Category: Paediatric Clinical
Winner: Dr Zarif Jabbar-Lopez, King’s College London, UK
Title: “Gene-environment interaction between filaggrin and hard water associated with increased risk of atopic eczema”
Poster number: O.009
Category: Basic Science
Winner: Ms Koyel Sengupta, Bose Institute, India
Title: “Identification of allergens from Trichoderma viride: an important biofungicide”
Poster number: P.097
Category: Allied Health
Winner: Dr Deborah Marriage, Bristol Royal Hospital for Children, UK
Title: “An audit of the prescription and use of adrenaline auto injector devices in adults and children”
Poster number: O.019
Category: Primary Care
Winner: Dr Melanie York, Sheffield Teaching Hospitals, UK
Title: “Non-specialist management and referral pathways in allergy”
Poster number: P.114
Winner: Ms Pooja Devani, Imperial College London, UK
Title: “Optimal mode of delivery for using probiotics or prebiotics to prevent eczema: a systematic review and meta-analysis”
Poster number: P.059
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William Frankland Award
The 2017 William Frankland Award was given to Professor George du Toit, London UK
Dr William Frankland, the “grandfather” of clinical allergy in the UK, is respected world wide for his contributions to allergy and particularly for his pioneering work on allergen specific immunotherapy which has improved the quality of life of patients with severe disease.
He was stunningly effective in providing grass pollen injections for thousands of severe hay fever sufferers at St Mary’s Hospital prior to World War Two, due to his excellent organizational abilities. In the post war years he demonstrated the efficacy of subcutaneous immunotherapy in a double blind placebo- controlled trial- thus becoming one of the first practitioners of evidence based medicine.
He also had the foresight to monitor pollen counts, having made an apparatus for the roof of St Mary’s, and then to broadcast this to the public and to the allergy community where it has proved of great worth in scientific studies. Dr Frankland proved prescient in choosing to work with colleagues from other disciplines: immunology, horticulture in order to further the progress of allergy understanding and treatment.
He was instrumental in the set up the British Society for Allergy & Clinical Immunology and served as Secretary and later President. He has also been President of the European Society of Allergology and is widely respected throughout the world for his clinical nous and his ground breaking research.
Jack Pepys Lecture
The 2017 Jack Pepys Lecture was given by Professor Anthony Frew, Brighton, UK
Professor Jack Pepys: 1914 -1996
Was Professor of Clinical Immunology at the Brompton Hospital in London from 1967 to 1979 and the “father” of British clinical allergy, He was an outstanding clinical researcher who made substantial contributions to the understanding of allergic diseases.
He had an ability to unravel complex mechanisms in specific allergic processes. An association between farmer’s lung and mouldy hay had been known since the 1930s, but the specific cause eluded people and there was much debate as to whether the disease was allergic in nature. Pepys and co-workers discovered a specific cause (allergy to moulds) and developed a blood test for farmer’s lung which has remained routine in clinical practice ever since.
Professor Pepys achieved international acclaim for his work on allergic bronchopulmonary aspergillosis and allergic lung diseases caused by fungi. These complex conditions were found by Professor Pepys and his team to have a basic immunological nature. This enabled them to explain the patterns of tissue destruction and develop further specific diagnostic tests. He also pioneered “experimental models” of provoked asthma and extrinsic allergic alveolitis in the clinical laboratory.
Having developed his lifelong interest in allergy and allergic diseases in 1948 he moved from South Africa to London and became clinical assistant to Professor J.G. Scadding at the Brompton Hospital. During the 1950s he set up an allergy clinic there which soon became world-renowned.
Professor Pepys further contributions were his studies on occupational asthma. He developed a series of simple inhalation tests which enabled a cause and effect relationship to be established between asthma and low molecular weight chemicals and other sensitising agents in the workplace. His published papers on platinum salts, isocyanates and colophony as occupational sensitising agents are classics of their time. Using serological tests he was able to set the scene for subsequent studies on the immunopathology of occupational asthma. This eventually led to occupational asthma’s being recognised as a compensatable industrial disease.
In 1971 he founded and was first editor of the journal Clinical Allergy (now Clinical and Experimental Allergy). He was a founder member and first Treasurer of the British Society for Immunology and President of the British Society for Allergy and Clinical Immunology, and the International Association of Allergology and Clinical Immunology.
Harry Morrow Brown Memorial Lecture
The 2016 Harry Morrow Brown Memorial Lecture was given by Professor Gideon Lack, London
Dr Harry Morrow Brown 1917-2013
Was born in Scotland, near Gleneagles. He qualified at Edinburgh University in 1939 and joined the army on October 1939. In 1942 he was drafted to India but finished in administration medical charge of half of Ceylon and was demobilised with the rank of Major. After various appointments in Scotland, he was appointed in 1953, as Consultant Chest Physician at Derby. At first, he was dealing mainly with tuberculosis but his interest soon changed to asthma and allergy.
A paper in the Lancet in 1958 showed that patients with asthma who responded to oral steroid depended on the presence of eosinophils for case selection. Based on this, some years later he had dramatic success with this trial being the first to show that inhaled steroids were therapeutic in asthma for which he gained international recognition. He wrote to the Lancet in 2010 about his first paper of fifty two years ago, stating that the paper would now never be published because ‘there is only one simple table of results, no statistics, no blinding of the investigator, no objective results from spirometry and only one author.’
He arranged a series of highly successful Charles Blackley Symposia at Derby. They became popular because the clinical rather than the academic side of allergy was discussed. He was interested in food allergy, but his main interest and greatest continued achievement was founding in 1968 of the Midlands Asthma and Allergy Research Association (MAARA). It funded research particularly developing strong teams in aerobiology.
He studied air spora by various means. He built volumetric and gravity slide methobiologic apparatus. He became interested in nano-particles and their role in pathology. He made a needle for skin prick testing which became commercially available. His microscope had many added attachments.
So much of what we should know about allergy and asthma start in children, or before they are born. Because of this interest, he has endowed a special lecture to be given in his name, every other year at the BSACI annual meeting.