Barry Kay Awards
This prestigious Award recognizes Professor Kay’s national and international research contributions to the field of allergy and asthma, which have inspired so many young Allergists and Chest Physicians.
There are six categories for this Award – Basic Science, Adult Allergy, Paediatric Allergy, Primary Care, Allied Health and Undergraduate. The 2021 winners for each category are listed below. To read the abstracts in full, please download the 2021 abstracts:
Category: Adult Clinical
Winner: Kok Loong UE, Guy’s and St Thomas’ NHS Foundation Trust, London UK
Title: Preliminary results of a phase II trial of peanut oral immunotherapy in adults
Poster number: 007
Category: Paediatric Clinical
Winner: Miss Dilini Kothalawala, University of Southampton, UK
Title: Predicting childhood asthma using machine learning and data integration approaches
Poster number: P.040
Category: Basic Science
Winner: Zohreh Babalou, Medica Lab and Allergy Centre, London
Title: The Association of Orosomucoid 1-like 3 (ORMDL3) Gene Polymorphism (rs12603332) with Susceptibility to Allergic Asthma in Iranian Northwestern Azeri Population.
Poster number: P023
Category: Allied Health
Winner: Rebecca Knibb, Aston University, Birmingham UK
Title: Preventing peanut allergy in East London – Audit of early peanut introduction amongst high risk infants
at The Royal London Hospital
Poster number: P019
Category: Primary Care
Winners: Matt Doyle, Indigo Medical, St Helier, Jersey/Shelley Dua, Cambridge University Hospitals
Title: Room for improvement in anaphylaxis and adrenaline autoinjector training: results from a UK primary care survey
Poster number: 023
Winner: Shriya Mehta, Imperial College London, UK
Title: Patterns of specialised formula consumption in Australia, England and Norway suggest significant milk allergy over-diagnosis
Poster number: P.20
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William Frankland Award
The 2021 William Frankland Award was given to Professor Graham Roberts, Southampton, UK
Dr Alfred William Frankland, MBE: 1912 -2020
Dr William Frankland, the “grandfather” of clinical allergy in the UK, was respected world wide for his contributions to allergy and particularly for his pioneering work on allergen specific immunotherapy which has improved the quality of life of patients with severe disease.
He was stunningly effective in providing grass pollen injections for thousands of severe hay fever sufferers at St Mary’s Hospital prior to World War Two, due to his excellent organizational abilities. In the post war years he demonstrated the efficacy of subcutaneous immunotherapy in a double blind placebo- controlled trial- thus becoming one of the first practitioners of evidence based medicine.
He also had the foresight to monitor pollen counts, having made an apparatus for the roof of St Mary’s, and then to broadcast this to the public and to the allergy community where it has proved of great worth in scientific studies. Dr Frankland proved prescient in choosing to work with colleagues from other disciplines: immunology, horticulture in order to further the progress of allergy understanding and treatment.
He was instrumental in the set up the British Society for Allergy & Clinical Immunology and served as Secretary and later President. He was also President of the European Society of Allergology and was widely respected throughout the world for his clinical nous and his ground breaking research.
Jack Pepys Lecture
The 2021 Jack Pepys Lecture was given by Dr Thirumala Krishna
Professor Jack Pepys: 1914 -1996
Jack Pepys was Professor of Clinical Immunology at the Brompton Hospital in London from 1967 to 1979 and the “father” of British clinical allergy, He was an outstanding clinical researcher who made substantial contributions to the understanding of allergic diseases.
He had an ability to unravel complex mechanisms in specific allergic processes. An association between farmer’s lung and mouldy hay had been known since the 1930s, but the specific cause eluded people and there was much debate as to whether the disease was allergic in nature. Pepys and co-workers discovered a specific cause (allergy to moulds) and developed a blood test for farmer’s lung which has remained routine in clinical practice ever since.
Professor Pepys achieved international acclaim for his work on allergic bronchopulmonary aspergillosis and allergic lung diseases caused by fungi. These complex conditions were found by Professor Pepys and his team to have a basic immunological nature. This enabled them to explain the patterns of tissue destruction and develop further specific diagnostic tests. He also pioneered “experimental models” of provoked asthma and extrinsic allergic alveolitis in the clinical laboratory.
Having developed his lifelong interest in allergy and allergic diseases in 1948 he moved from South Africa to London and became clinical assistant to Professor J.G. Scadding at the Brompton Hospital. During the 1950s he set up an allergy clinic there which soon became world-renowned.
Professor Pepys further contributions were his studies on occupational asthma. He developed a series of simple inhalation tests which enabled a cause and effect relationship to be established between asthma and low molecular weight chemicals and other sensitising agents in the workplace. His published papers on platinum salts, isocyanates and colophony as occupational sensitising agents are classics of their time. Using serological tests he was able to set the scene for subsequent studies on the immunopathology of occupational asthma. This eventually led to occupational asthma’s being recognised as a compensatable industrial disease.
In 1971 he founded and was first editor of the journal Clinical Allergy (now Clinical and Experimental Allergy). He was a founder member and first Treasurer of the British Society for Immunology and President of the British Society for Allergy and Clinical Immunology, and the International Association of Allergology and Clinical Immunology.
Harry Morrow Brown Memorial Lecture
The Harry Morrow Brown Memorial Lecture 2020 was given by Dr Michael Perkin, UK
Dr Harry Morrow Brown 1917-2013
Henry Morrow was born in Scotland, near Gleneagles. He qualified at Edinburgh University in 1939 and joined the army on October 1939. In 1942 he was drafted to India but finished in administration medical charge of half of Ceylon and was demobilised with the rank of Major. After various appointments in Scotland, he was appointed in 1953, as Consultant Chest Physician at Derby. At first, he was dealing mainly with tuberculosis but his interest soon changed to asthma and allergy.
A paper in the Lancet in 1958 showed that patients with asthma who responded to oral steroid depended on the presence of eosinophils for case selection. Based on this, some years later he had dramatic success with this trial being the first to show that inhaled steroids were therapeutic in asthma for which he gained international recognition. He wrote to the Lancet in 2010 about his first paper of fifty two years ago, stating that the paper would now never be published because ‘there is only one simple table of results, no statistics, no blinding of the investigator, no objective results from spirometry and only one author.’
He arranged a series of highly successful Charles Blackley Symposia at Derby. They became popular because the clinical rather than the academic side of allergy was discussed. He was interested in food allergy, but his main interest and greatest continued achievement was founding in 1968 of the Midlands Asthma and Allergy Research Association (MAARA). It funded research particularly developing strong teams in aerobiology.
He studied air spora by various means. He built volumetric and gravity slide methobiologic apparatus. He became interested in nano-particles and their role in pathology. He made a needle for skin prick testing which became commercially available. His microscope had many added attachments.
So much of what we should know about allergy and asthma start in children, or before they are born. Because of this interest, he has endowed a special lecture to be given in his name, every other year at the BSACI annual meeting.